Laboratory Frits

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Hydrophilic Frits for Protein Purification Columns Gravity Columns Affinity Chromatography Columns

Hydrophilic frit: generally refers to the reaction between reactive functional groups attached to a solid-phase carrier (e.g., resin, etc.) and a reagent dissolved in an organic solvent. It is a hydrophobic material made of ultra-high molecular weight polyethylene (UHMW-PE) sintered by modifying the surface with a hydrophilic agent.
B&M® Hydrophilic Frits Hydrophilic UHWMPE production technology is applied; the hydrophilicity of the frits for affine chromatography columns has been specially treated for wetting with aqueous solutions; This is very advantageous when filtering aqueous solutions.
In solid-phase peptide synthesis, the peptide chain is elongated on an insoluble polystyrene resin carrier. The C-terminal portion of the synthetic peptide is first reacted with chloromethylpolystyrene resin (ester resin) to form a benzyl ester, and then the amino acids protected at the amino terminal are added one by one in the order of the primary structure of the peptide chain to elongate the peptide chain. The solid-phase method is simpler and shorter than the liquid-phase method and can be automated. It is used in our pharmaceutical industry.

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Material properties of UHMW-PE

Ultra-high molecular weight polyethylene (UHMW-PE) is a polyethylene with a molecular weight of more than 1.5 million and is a thermoplastic engineering plastic with excellent comprehensive performance.

UHMW-PE has excellent impact resistance, wear resistance, low temperature resistance and self-lubricating properties, and has the following excellent performance:

● Excellent chemical resistance: In addition to strong oxidizing acids, it can withstand a variety of corrosive environments (acids, alkalis, salts) and organic environments (except naphthalene solvents) within a certain temperature and concentration range.

● Hygienic and non-toxic: physiologically inert and physiologically adaptable, meet the standards of the International Health Association, can be used in contact with food and medicine, and functional parts can be implanted in the human body.

● Excellent Hydrophobicity: UHMW-PE has a very low water absorption rate of less than 0.01%, only 1% of Nylon 66, which is one of the lowest water absorption rates among engineering plastics.

Ultra High Molecular Weight Polyethylene Particle Size Selection

The particles of UHMW-PE material are not standard spherical, the more uniform the particle size of the material, the closer it is to spherical, the better the uniformity and the higher the quality of the sintered cartridge. BM Life Sciences has set strict standards for the selection of raw materials, and sintered cartridges are made of materials with uniform particle size, and for special requirements, we use materials with uniform particle size that are not spherical to ensure the high quality of sintered cartridges.

UHMWPE Cleanliness Control

BM Life Sciences offers two types of raw materials: 1) pure raw materials that meet the medical standard; 2) ultra-pure raw materials, which are purified by distillation of various organic solvents and used for highly sensitive chromatographic analysis.

Quality Assurance

B&M® filter cartridges/frits are made of pure ultra-high molecular weight polyethylene (UHMW-PE) and polypropylene (PP) sintered to suit different application scenarios, or polyester fiber, polypropylene fiber, PTFE, or a combination of two or more materials for special applications.

BM Life Science Laboratory conducts testing and research in the field of life sciences, chemical analysis, materials science, etc.

Order Details

Product Number	Description	calibre	Thickness	Hole Diameter	Packing (/bag)
LF021-25-020	96-well frit for hydrophilic substances	2.1±0.05mm	2.5±0.15mm	20±10um	1000
LF025-16-020	96-well frit for hydrophilic substances	2.5±0.05mm	1.6±0.15mm	20±10um	1000
LF023-16-020	Column plates for ultra-micro affine centrifuge	2.3±0.05mm	1.6±0.15mm	20±10um	1000
LF023-25-020	Column plates for ultra-micro affine centrifuge	2.3±0.05mm	2.5±0.15mm	20±10um	1000
LF051-16-020	Column plates for ultra-micro affine centrifuge	5.15±0.05mm	1.6±0.15mm	20±10um	1000
LF051-25-020	Column plates for ultra-micro affine centrifuge	5.15±0.05mm	2.5±0.15mm	20±10um	1000
LF058-16-050	1 ml Affinity Chromatography of Empty Column Frit	5.8±0.05mm	1.6±0.15mm	50±15um	1000
LF058-25-050	1 ml Affinity Chromatography of Empty Column Frit	5.8±0.05mm	2.5±0.15mm	50±15um	1000
LF060-16-050	3ml 96-well frit for hydrophilic substances	-	-	-	1000
LF060-25-050	3ml 96-well frit for hydrophilic substances	-	-	-	1000
LF069-25-050	1ml 96-well frit for hydrophilic substances	6.9±0.05mm	2.5±0.15mm	50±15um	1000
LF070-16-050	1ml 96-well frit for hydrophilic substances	7.0±0.05mm	1.6±0.15mm	50±15um	1000
LPF072-10-05	1 ml Affinity Chromatography of Empty Column Frit	7.2±0.05mm	1.0±0.15mm	5±3um	1000
LPF078-10-05	1 ml Affinity Chromatography of Empty Column Frit	7.8±0.05mm	1.0±0.15mm	5±3um	1000
LF072-16-050	2ml 96-well frit for hydrophilic substances	7.22±0.05mm	1.6±0.15mm	50±15um	1000
LF072-16-100	2ml 96-well frit for hydrophilic substances	7.22±0.05mm	1.6±0.15mm	100±20um	1000
LF072-25-050	2ml 96-well frit for hydrophilic substances	7.22±0.05mm	2.5±0.15mm	50±15um	1000
LF074-16-050	2ml 96-well frit for hydrophilic substances	7.4±0.05mm	1.6±0.15mm	50±15um	1000
LF074-25-050	2ml 96-well frit for hydrophilic substances	7.4±0.05mm	2.5±0.15mm	50±15um	1000
LF076-16-050	3ml 96-well frit for hydrophilic substances	7.6±0.05mm	1.6±0.15mm	50±15um	1000
LF076-16-100	3ml 96-well frit for hydrophilic substances	7.4±0.05mm	1.6±0.15mm	100±20um	1000
LF079-16-050	2ml 96-well frit for hydrophilic substances	7.9±0.05mm	1.6±0.15mm	50±15um	1000
LF079-16-100	2ml 96-well frit for hydrophilic substances	7.9±0.05mm	1.6±0.15mm	100±20um	1000
LF080-16-050	1 ml Affinity Chromatography of Empty Column Frit	8.0±0.05mm	1.6±0.15mm	50±15um	1000
LF081-16-050	1.5ml 96-well frit for hydrophilic substances	8.1±0.05mm	1.6±0.15mm	50±15um	1000
LF081-25-050	1.5ml 96-well frit for hydrophilic substances	8.1±0.05mm	2.5±0.15mm	50±15um	1000
LF090-16-020	3 ml Affinity Chromatography of Empty Column Frit	9.0±0.05mm	1.6±0.15mm	20±10um	1000
LF090-16-050	3 ml Affinity Chromatography of Empty Column Frit	9.0±0.05mm	1.6±0.15mm	50±15um	1000
LF090-25-050	3 ml Affinity Chromatography of Empty Column Frit	9.0±0.05mm	2.5±0.15mm	50±15um	1000
LF091-16-020	3 ml Affinity Chromatography of Empty Column Frit	9.1±0.05mm	1.6±0.15mm	20±10um	1000
LF091-16-050	3 ml Affinity Chromatography of Empty Column Frit	9.1±0.05mm	1.6±0.15mm	50±15um	1000
LF091-25-050	3 ml Affinity Chromatography of Empty Column Frit	9.1±0.05mm	2.5±0.15mm	50±15um	1000
LF130-16-020	6 ml Affinity Chromatography of Empty Column Frit	13.0±0.05mm	1.6±0.15mm	20±10um	1000
LF130-16-050	6 ml Affinity Chromatography of Empty Column Frit	13.0±0.05mm	1.6±0.15mm	50±15um	1000
LF130-25-020	6 ml Affinity Chromatography of Empty Column Frit	13.0±0.05mm	2.5±0.15mm	20±15um	1000
LF130-25-050	6 ml Affinity Chromatography of Empty Column Frit	13.0±0.05mm	2.5±0.15mm	50±15um	1000
LF158-16-020	6 ml Affinity Chromatography of Empty Column Frit	15.8±0.05mm	1.6±0.15mm	20±10um	1000
LF158-16-050	6 ml Affinity Chromatography of Empty Column Frit	15.8±0.05mm	1.6±0.15mm	50±15um	1000
LF158-25-020	12 ml Affinity Chromatography of Empty Column Frit	15.8±0.05mm	2.5±0.15mm	20±15um	1000
LF158-25-050	12 ml Affinity Chromatography of Empty Column Frit	15.8±0.05mm	2.5±0.15mm	50±15um	1000
LPF162-10-05	5 ml Affinity Chromatography of Empty Column Frit	16.2±0.05mm	10±0.15mm	5±3um	1000
LF169-16-050	5 ml Affinity Chromatography of Empty Column Frit	16.9±0.05mm	1.6±0.15mm	50±15um	1000
LPF171-10-05	5 ml Affinity Chromatography of Empty Column Frit	17.1±0.05mm	10±0.15mm	5±3um	1000
LF196-25-020	20 ml Affinity Chromatography of Empty Column Frit	19.6±0.05mm	2.5±0.15mm	20±15um	1000
LF196-25-050	20 ml Affinity Chromatography of Empty Column Frit	19.6±0.05mm	2.5±0.15mm	50±15um	1000
LF236-25-020	30 ml Affinity Chromatography of Empty Column Frit	23.6±0.05mm	2.5±0.15mm	20±15um	1000
LF236-25-050	30 ml Affinity Chromatography of Empty Column Frit	23.6±0.05mm	2.5±0.15mm	50±15um	1000
LF266-25-020	60 ml Affinity Chromatography of Empty Column Frit	26.6±0.05mm	2.5±0.15mm	20±15um	1000
LF266-25-050	60 ml Affinity Chromatography of Empty Column Frit	26.6±0.05mm	2.5±0.15mm	50±15um	1000
LF386-25-020	150 ml Affinity Chromatography of Empty Column Frit	38.6±0.05mm	2.5±0.15mm	20±15um	1000
LF386-25-050	150 ml Affinity Chromatography of Empty Column Frit	38.6±0.05mm	2.5±0.15mm	50±15um	1000
LF504-25-020	300 ml Affinity Chromatography of Empty Column Frit	50.4±0.05mm	2.5±0.15mm	20±15um	1000
LF504-25-050	300 ml Affinity Chromatography of Empty Column Frit	50.4±0.05mm	2.5±0.15mm	50±15um	1000
LF666-25-020	550 ml Affinity Chromatography of Empty Column Frit	66.6±0.05mm	2.5±0.15mm	20±15um	1000
LF666-25-050	550 ml Affinity Chromatography of Empty Column Frit	66.6±0.05mm	2.5±0.15mm	50±15um	1000
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